HISTOMORPHOLOGY AND IMMUNOHISTOCHEMISTRY OF A CONGENITAL NEPHROMEGALY DEMONSTRATE CONCURRENT FEATURES OF HERITABLE AND ACQUIRED CYSTIC NEPHROPATHIES IN A GIRGENTANA GOAT (CAPRA FALCONERI)

Histomorphology and Immunohistochemistry of a Congenital Nephromegaly Demonstrate Concurrent Features of Heritable and Acquired Cystic Nephropathies in a Girgentana Goat (Capra falconeri)

Polycystic kidney diseases (PKD) represent frequent congenital and adult nephropathies in humans and domestic animals.This report illustrates an uncommon state of congenital PKD in a girgentana goat (Capra falconeri).A stillborn female goat kid was submitted for postmortem examination and underwent macroscopic and microscopic examination.The kidney

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Kernel-based genetic association analysis for microbiome phenotypes identifies host genetic drivers of beta-diversity

Abstract Background Understanding human genetic influences on the gut microbiota helps elucidate the mechanisms by which genetics may influence health outcomes.Typical microbiome genome-wide association studies (GWAS) marginally assess the association between individual genetic variants and individual microbial taxa.We propose a novel approach, the

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